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Not all biopsies are created equal – newer methods are safer and more reliable

Prostate Biopsy

With over two decades of experience as a urologist and men's health specialist, I have successfully guided countless men through the prostate cancer diagnosis journey. A crucial step in this process is the Prostate Biopsy, and the methods for conducting this test have evolved significantly over the years.

Let me walk you through how things have evolved and what that means for you or someone you care about.

Why We Do a Prostate Biopsy

As of early 2025, a biopsy remains the gold standard for diagnosing prostate cancer. A biopsy involves taking a small sample of prostate tissue to look for cancer cells.

Historically, we relied mainly on:

  • PSA blood tests

  • Physical prostate exams

If either test was abnormal, the next step was a biopsy – often done without imaging guidance, meaning we couldn’t see exactly where to aim. That has changed.

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How Imaging Has Changed the Game

Today, we use:

  • MRI scans

  • PSMA PET scans

These imaging tools give us detailed information about the prostate and allow us to:

  • Pinpoint where a suspicious area is

  • Estimate the risk of cancer

  • Target that area during biopsy

This means more accurate diagnoses and fewer unnecessary biopsies.

There are Two main Types of Biopsy Techniques

Aspect

Transrectal Biopsy

Transperineal Biopsy

Needle Path

Through the rectum

Through the skin near the perineum

Common Location

North America

Australia (standard since 2010)

Setting

In-office

In hospital

Anaesthesia

Local anaesthetic

General anaesthetic

Infection Risk

Up to 6–7%

Extremely low

Advantages

Convenient, widely used

Safer, lower infection risk, increasingly preferred globally

Usage Trend

Still common but being reconsidered due to infection risk

Growing in popularity due to improved safety profile

Our focus has always been on safety and accuracy, and the Transperineal approach reflects this perfectly. At the Prostate Clinic, we've used this method for more than 15 years, completing many procedures without any infections. It's been a dependable choice throughout our journey.

Image-Guided Biopsies: Even More Accuracy - Newer techniques help us improve accuracy even further:

Cognitive Fusion Biopsy

  • The urologist reviews the MRI scan and “mentally fuses” it with the real-time ultrasound image during the biopsy.

Artemis Fusion Biopsy

  • We use software to match MRI scans with real-time ultrasound images

  • This helps us accurately target specific areas of concern

These techniques mean better sampling and a reduced chance of missing cancer that’s actually there.

What This Means for You

If you or someone close to you is facing a prostate biopsy:

  • Ask whether imaging (like an MRI) has been done first

  • Discuss the Transperineal approach with your specialist

  • Understand that not all biopsies are created equal – newer methods are safer and more reliable

We're Here to Help

We understand that this process can feel overwhelming. Our team is here to guide you every step of the way. At the Prostate Health Clinic, we've empowered thousands of men to take charge of their health with confidence. If you're eager to learn more or dive into your options, reach out to us today; whether you have questions or want to chat about your unique situation, feel free to contact us to book a consultation.

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